The nation's top scientists come together to put a stop to the recent phenomenon of rich, successful men who suddenly want to have sex with many, many women. After extensive testing, some of the fourth grade boys in South Park Elementary are diagnosed as sex addicts. It is shown in teaser pictures that Tiger Woods will appear in the episode as well as David Letterman, Ben Roethlisberger, Bill Clinton, Billy Bob Thornton and Michael Douglas.

The students at South Park Elementary are assigned to read The Catcher In The Rye, and are excited to do so after learning about the controversy surrounding the book. However, Stan, Kyle, Cartman, and Kenny hate the novel, not finding it offensive and wondering why it was banned in public schools. They decide to write their own novel, entitled The Tale of Scrotie McBoogerballs, with the intention of making it the most profane and controversial book ever.

Cartman's favorite restaurant has been shut down and replaced by a store that sells medicinal marijuana. Randy is desperate to get a prescription card to buy pot and Cartman will do anything to get his beloved fried chicken back.

Kyle "friended" the wrong person (on Facebook) and now all of his old friends are deserting him. His situation is desperate. Kyle looks for help from the one person who has always been there for him.

While on a school field trip to a fudge factory, Stan accidentally insults Tom Cruise again by calling him a "fudge packer" and sets off a chain reaction. Cruise then recruits every celebrity that has ever been ridiculed by the town of South Park to bring a class action lawsuit against the town. (Part 1 of 2)

With Muhammad at the center of hostage negotiations between the town of South Park and both the Ginger kids and Tom Cruise's army of celebrities, the burning question on everyone's mind is... Who is Eric Cartman's father?!. (Part 2 of 2)

Jimmy and Timmy head off to summer camp with all their "handi-capable" friends, competition is the name of the game this summer. Meanwhile, Towelie, addicted to marijuana, crack, and crystal meth, is part of a documentary. He works at the handicapped summer camp, and is later fired. As his story unfolds, he is later faced with an intervention.